Brenda M. Ryals, Ph.D.

Professor
Editor-in-Chief, Ear & Hearing

Office: HHS 1145
Phone: 568-3871
Email: ryalsbm@jmu.ed

Research and Teaching Areas

Anatomy and Physiology of the Auditory System
Auditory plasticity in the periphery - hair cell regeneration
Central auditory system plasticity as a function of hair cell regeneration or deprivation

Research Laboratory

Auditory Research Laboratory

Current and Ongoing Research Projects

Functional consequences o f hair cell regeneration
Afferent and efferent hair cell innervation patterns after regeneration or during development in hereditary hearing loss
Central auditory system re-organization in an avian model with ongoing hair cell regeneration and hereditary hearing loss

Publications (last five years)

Ryals, Brenda M, Svirsky , Mario A. (2008) Editorial Note Regarding Sufficiency of Authors' Disclosures: Hearing Levels of Firefighters: Risk of Occupational Noise-Induced Hearing Loss Assessed by Cross-Sectional and Longitudinal Data, [Ear Hear 2005;26(3):327-340] Ear & Hearing. 29(5):815-816, October 2008.

Dooling, RJ,Dent, ML, Lauer, AM and Ryals, BM (2008) Functional Recovery Following Hair Cell Regeneration in Birds in, Hair Cell Regeneration, Repair, and Protection (pp. 117-140).Salvi, R. J., Popper, A. N., and Fay, R. R. (eds). Springer Science+Business Media, LLC, New York

Ryals, B.M., Matsui, J.I., Cotanche, D.A., (2007) Regeneration of Hair Cells. In Pharmacology and Ototoxicity for Audiologists (pp301-319), C.M. Campbell ed., Thompson Delmar Learning, New York

Dooling, RJ, Ryals, BM, Dent, ML and Reid, TL (2006) Perception of Complex Sounds in Budgerigars (Melopsittacus undulates) with Temporary Hearing Loss, Journal of the Acoustical Society 119(4):1-9.

Matsui, J. and Ryals, BM (2006) Hair cell regeneration: An exciting phenomenon, but will it be possible to restore hearing and balance? Journal of Rehabilitation Research and Development 42(4):187-198

Marler, JA, Elfenbein, JL, Ryals, BM, Urban, Z. and Netzloff, ML (2005) Sensorineural hearing loss in children and young adults with Williams Syndrome, American Journal of Medical Genetics 138(4):318-27

Matsui, J., Parker, MA., Ryals, BM and Cotanche DA (2005) “Regeneration and Replacement in the Vertebrate Inner Ear” Drug Discovery Today 10(19):1307-12

National and International Conference Presentations (last five years)

Ryals, BM (2009) Improving the effectiveness/efficiency of clinical audiology education by controlling the clinical experience …, AAA Gold Standards Summit, Orlando, Florida.

Ryals, B.M. Current Frontiers in the Field of Audiology, Danish Technical Audiology Society, Vejle, Denmark, 2008

Ryals, BM. Hair cell regeneration: What is the potential for therapeutic intervention?, Danish Technical Audiology Society, Vejle, Denmark, 2008

Ryals, BM (2008) Functional changes after hair cell regeneration, International Conference on Cell Replacement in the Inner Ear, funded by the DRF and NIDCD, Bethesda MD

Ryals, BM (2008, March) Hair cell regeneration: What is the potential for therapeutic intervention? Invited presentation, National Association of Future Doctors of Audiology National Convention, Charlotte, NC

Ryals, BM, (2007, October) Hair cell regeneration: What is the therapeutic potential? Keynote presentation, Canadian Academy of Audiology, Ontario CA

Ryals, BM, Dooling, RJ Perceptual Consequences of Hair Cell Regeneration, presented at the international meeting of the Collegium Oto-Rhino-Laryngologgicum Amicitiae Sacrum (CORLAS) meeting, Moscow Russia September 2006

Ryals BM, Sanovich E, Petralia RS, Dooling RJ, TEM Analysis of the Synaptic Consequences of Hair Cell Loss and Regeneration in a Bird with Progressive, Genetic Inner Ear Abnormality, poster presentation at the international Inner Ear Biology meeting, Montpellier, France, September 2006

Ryals, BM, “What Audiologists Need (Want?) to Know About Hair Cell Regeneration, West Virginia State Speech Hearing Language Association March 2006

Ryals, BM “Hair Cell Regeneration: What is the potential for therapeutic intervention?”
Fourth Annual Widex InternationalCongress on Pediatric Audiology, Ottowa Canada May 2006

Marler, JA, Elfenbein, JL, Ryals, BM and Netzloff, ML, Sensorineural Hearing Loss In Children And Young Adults With Williams Syndrome, International Evoked Response Audiometry Study Group (IERASG) Biennial Symposium, Havana Cuba, June 2005.

Ratner, NB, Davidson, S., Diefendorf, A, Goldstein, H, Kent, R., Ryals, B., Shepard, N., A rewarding career in academia, American Speech Language Hearing Assoc. annual convention, San Diego, CA Nov. 17-20, 2005

Marler, JA, Elfenbein, JL, Ryals, BM, Urban, Z, Netzloff, ML. Auditory Acuity in Williams Syndrome and Supravalvular Aortic Stenosis, American Speech Language Hearing Assoc. annual convention, San Deigo CA Nov. 17-20, 2005

Wright, KL, Ryals, BM, Hearing Screening in Special Olympics Athletes: Follow-up, poster presentation American Academy of Audiology March 2005

Ryals, BM. (moderator and panelist) special Symposium sponsored by ASHA at the national convention of the American Academy for the Advancement of Science: “Restoring Damaged Inner Ear Hair Cells and Their Neural Connections”, Speakers J. Stone U. Washington, N. Segil House Ear Inst. And S. Green, Univ. Iowa, Feb. 2005